Hungry for more family-friendly recipes? Sign up for my free recipe club to get new family-friendly recipes in your inbox each week! Find me sharing daily meal-time inspiration on Pinterest and Instagram.

Spatula getting salsa chicken out of casserole dish

Creamy Salsa Chicken

This Creamy Salsa Chicken combines tender chicken breast with rich salsa, tangy sour cream, and two cheeses for a Mexican inspired meal that everyone enjoys! It is all baked in just one casserole dish for easy prep and even easier clean up!
Print Pin This


  • 2 lbs chicken breast boneless, skinless - thinly sliced
  • 8 oz cream cheese softened
  • 1/2 cup sour cream
  • 1 cup salsa
  • 1 cup cheddar cheese shredded

Garnish (optional)

  • cilantro chopped


  • Preheat the oven to 375˚F.
  • Lay the chicken breast flat in a large baking dish.
  • Mix the cream cheese, sour cream, and salsa together until combined. Then spread over the chicken.
  • Top with cheddar cheese. Then bake for 25-35 minutes or until the chicken is cooked through (165˚F internal temp.)
  • Remove from oven and garnish with cilantro if desired. Enjoy!

Nutrition Information:

Calories: 427kcal (21%)Carbohydrates: 5g (2%)Protein: 40g (80%)Fat: 27g (42%)Saturated Fat: 14g (88%)Cholesterol: 168mg (56%)Sodium: 735mg (32%)Potassium: 781mg (22%)Fiber: 1g (4%)Sugar: 4g (4%)Vitamin A: 1070IU (21%)Vitamin C: 2.8mg (3%)Calcium: 214mg (21%)Iron: 1mg (6%)

(Nutrition information provided is an estimate and will vary based on cooking methods and brands of ingredients used.)